Frequently Asked Questions

Results - General Questions

GeneAnalytics identifies tissues, cells, diseases, molecular pathways, GO biological process and molecular function and compounds that match the query gene set.

The full list of matched genes can be viewed by clicking on the number of matched genes for each entity in the table. The list of matched genes in the pop up window can be used for a new GeneAnalytics query. 

The GeneAnalytics analysis is based on proprietary, comprehensive and organized databases which are part of the LifeMap suite.

The following table summarizes the data sources for each section in GeneAnalytics. For more details, see Resources and statistics.


SectionUnderlying databases
Tissues & cells LifeMap Discovery®-the embryonic development and stem cells compendium
Diseases Malacards-the human malady compendium
Pathways PathCards-the human biological pathway unification
GO terms GeneCards®-the human gene compendium
Compounds GeneCards-the human gene compendium

Individual entity scores are classified as high, medium or low. This classification is indicated by the color of the score bar (dark green, light green or beige, respectively).  The distribution of the scores can be viewed by clicking on the pie icon.

  • In the tissues & cells and the diseases sections, the classification of the matching scores is based upon an empirical examination of many test cases, and is different for each query size.
  • In the pathways, GO terms and compounds sections, the score is a transformation of the binomial distribution p-value and the score range is divided into three quality levels, according to the p-value they are derived from (after correction for multiple comparisons), as following:
  • High: corrected p-value smaller or equal to 0.05.
  • Medium: corrected p-value higher than 0.05 but smaller or equal to 1.
  • Low: corrected p-value higher than 1.

In the detailed results table, clicking on the entity (e.g., cell, tissue, disease) name reverts you to the entity card in the underlying database. Specifically, you will be directed to the gene section in the relevant card.

In addition, the full list of matched genes can be viewed by clicking on the ‘number of matched genes’ for each entity in the table. In the tissues & cells results, the matched gene list includes an indication whether this information is derived directly from scientific manuscripts, high throughput gene expression comparisons, or large scale datasets. In the diseases section, the matched gene lists includes an indication for the gene-disease relations.


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