How can I identify cell markers and genes that are specific or enriched within a specific organ/tissue?

• You can view annotations for selective cell markers by clicking on the number of matched genes for a specific cell in the results table. Matched genes that serve as cellular markers are indicated by the following icon: .
• To view genes in your query that are annotated as abundant or housekeeping genes, go to the ‘Analyzed genes’ panel at the top of the results page, and click on  . Abundant genes are genes that appear in a large number of organs or tissues in LifeMap Discovery (for more information about LifeMap Discovery entities, click here). Housekeeping genes are genes contained within a list that was established by integrating information from several studies aimed to identify human housekeeping genes.
• The LifeMap Discovery database contains more gene annotations which are not yet presented to the user but are used for the GeneAnalytics calculations:
  • Specific gene: a gene that is specific to or is expressed in only a few organs or tissues.  
  • Enriched gene: a gene that is expressed in many entities of the same organ or tissue.

To receive a list of all genes expressed in a specific tissue, organ or developmental path, including annotations for selective markers, specific genes and tissue-enriched genes, please contact us.